Institut Pasteur de Lille Unité d'Epidémiologie et de Santé Publique INSERM UMR744 BP 245 59019 LILLE Cedex - FRANCE Phone : +33 (0)3 20 87 78 01 Fax : +33 (0)3 20 87 78 94 Email Nicole HELBECQUE INSERM Research Director Curriculum Vitae Date of birth: 27 November 1948, Lille, France French nationality Diploma Baccalauréat Mathématiques Elémentaires (1965) Chemical Engineer (HEI, 1969) Post-graduate diploma in Physical Chemistry (1970) PhD in Physical Chemistry (1972) Doctorat d'Etat ès Sciences Physiques (1979) Scientific Activities 1969-1972 : PhD in Physical Chemistry at the Laboratory of Macromolecular Chemistry, University Lille 1 - Synthesis and study of the optical activity of peptides. 1972-1973 : Post-doc at the 'Wollforschung Institut an der technischen Universität Aachen' (Pr H. Zahn) - Contribution to the synthesis of insulin synthesis. 1974-1979 : Doctorat d'Etat ès Sciences Physiques at University of Lille 2 - Synthesis and conformational study of peptides and polypeptides models of PRP. 1979 : Post-doc at the Laboratory of Pharmacology, University of Sherbrooke, Canada (Pr S. Saint-Pierre) - Solid phase peptide synthesis. 1979 : University of Lille 2 (Pr G. Biserte) - Synthesis and study of biologically active peptides. Synthesis and study of the mode of action of antitumoral drugs. 1990 : Research Director at INSERM. 1993 : INSERM U325, then CJF95-05, then U508 - Role of vascular risk factors in the occurrence of neurodegenerative disorders.   Professional Experience INSERM Research Engineer (1976-1990) INSERM Research Technician (1974-1976)